(-)-Bicuculline methobromide

• Supplier: Tocris Bioscience
• Catalog: 2503
• Prices: $99.00, $419.00
• Sizes: 10 mg, 50 mg
• Cas Number: 73604-30-5
• Chemical Name: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinoliniumbromide
• Formula: C21H20BrNO6
• Molecular Weight: 462.3
• Purity: >98 %
• Description: Methobromide salt of (+)-bicuculline (Cat. No. 0130). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

Product References

Characteristics of GABAB receptor binding sites on rat whole brain synaptic - Characteristics of GABAB receptor binding sites on rat whole brain synaptic

Bowery NG, Hill DR, Hudson AL. Br J Pharmacol. 1983 Jan;78(1):191-206.

Nigral infusions of muscimol or bicuculline facilitate seizures in developing - Nigral infusions of muscimol or bicuculline facilitate seizures in developing

Sperber EF, Wong BY, Wurpel JN, Moshe SL. Brain Res. 1987 Dec 15;465(1-2):243-50.

Recent advances in the pharmacology of quaternary salts of bicuculline. - Recent advances in the pharmacology of quaternary salts of bicuculline.

Seutin V, Johnson SW. Trends Pharmacol Sci. 1999 Jul;20(7):268-70.