(-)-Bicuculline methochloride

• Supplier: Tocris Bioscience
• Catalog: 0109
• Prices: $115.00, $449.00
• Sizes: 10 mg, 50 mg
• Cas Number: 53552-05-9
• Chemical Name: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinoliniumchloride
• Formula: C21H20ClNO6
• Molecular Weight: 417.85
• Purity: >99 %
• Description: Methochloride salt of (+)-bicuculline (Cat. No. 0130). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

Product References

Quantitative evaluation of the potencies of GABA-receptor agonists and - Quantitative evaluation of the potencies of GABA-receptor agonists and

Kemp JA, Marshall GR, Woodruff GN. Br J Pharmacol. 1986 Apr;87(4):677-84.

Evidence for a non-GABAergic action of quaternary salts of bicuculline on - Evidence for a non-GABAergic action of quaternary salts of bicuculline on

Seutin V, Scuvee-Moreau J, Dresse A. Neuropharmacology. 1997 Nov-Dec;36(11-12):1653-7.

Recent advances in the pharmacology of quaternary salts of bicuculline. - Recent advances in the pharmacology of quaternary salts of bicuculline.

Seutin V, Johnson SW. Trends Pharmacol Sci. 1999 Jul;20(7):268-70.