(+)-Bicuculline

• Supplier: Tocris Bioscience
• Catalog: 0131
• Prices: $199.00
• Sizes: 50 mg
• Function Type: Antagonist
• Cas Number: 485-49-4
• Chemical Name: [R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one
• Formula: C20H17NO6
• Molecular Weight: 367.36
• Purity: >99 %
• Description: Classical GABA A antagonist. Methoiodide salt (Cat. No. 2503), Methobromide salt (Cat. No. 0109) and Methochloride salt (Cat. No. 0131) also available.

Product References

GABA, bicuculline and central inhibition. - GABA, bicuculline and central inhibition.

Curtis DR, Duggan AW, Felix D, Johnston GA. Nature. 1970 Jun 27;226(5252):1222-4.

Studies on the neuropharmacological activity of bicuculline and related - Studies on the neuropharmacological activity of bicuculline and related

Olsen RW, Ban M, Miller T. Brain Res. 1976 Feb 6;102(2):283-99.

Intracerebral site of convulsant action of bicuculline. - Intracerebral site of convulsant action of bicuculline.

Piredda S, Lim CR, Gale K. Life Sci. 1985 Apr 1;36(13):1295-8.

Multiplicity of GABAA--benzodiazepine receptors. - Multiplicity of GABAA--benzodiazepine receptors.

Sieghart W. Trends Pharmacol Sci. 1989 Oct;10(10):407-11.