BIMU 8

• Supplier: Tocris Bioscience
• Catalog: 1844
• Prices: $185.00, $755.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 134296-40-5
• Chemical Name: 2,3-Dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamidehydrochloride
• Formula: C19H26N4O2.HCl
• Molecular Weight: 378.9
• Purity: >98 %
• Description: Potent 5-HT 4 receptor full agonist (K D = 77 nM and EC 50 = 18 nM for wild type 5-HT 4 receptors). Binds to receptors in a mechanism different to that of the endogenous ligand 5-HT.

Product References

Blockade of feeding inhibition by neuromedin B using a selective receptor - Blockade of feeding inhibition by neuromedin B using a selective receptor

Ladenheim EE, Taylor JE, Coy DH, Moran TH. Eur J Pharmacol. 1994 Dec 12;271(1):R7-9.

The neuromedin B receptor antagonist, BIM-23127, is a potent antagonist at human - The neuromedin B receptor antagonist, BIM-23127, is a potent antagonist at human

Herold CL, Behm DJ, Buckley PT, Foley JJ, Wixted WE, Sarau HM, Douglas SA. Br J Pharmacol. 2003 May;139(2):203-7.

Blockade of bombesin-like peptide receptors impairs inhibitory avoidance learning - Blockade of bombesin-like peptide receptors impairs inhibitory avoidance learning

Santo-Yamada Y, Yamada K, Wada E, Goto Y, Wada K. Neurosci Lett. 2003 Apr 3;340(1):65-8.