Name | Bis-ANS |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4776 |
Prices | $135.00 |
Sizes | 10 mg |
Cas Number | 65664-81-5 |
Chemical Name | 4,4'-Bis(phenylamino)-[1,1'-binaphthalene]-5,5'-disulfonicaciddipotassiumsalt |
Formula | C32H22K2N2O6S2 |
Molecular Weight | 672.85 |
Purity | >97 % |
Description | Fluorescent probe for nonpolar cavities in proteins. Used to detect A β fibre (K d = ~80 nM); exhibits distinct fluorescent profiles for fibres and oligomers. Fluoresces in hydrophobic environments, negligible fluorescence in water solutions. Excitation\emission λ ~ 355\520 nm at pH 7.4. |
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Newman AH, Allen AC, Izenwasser S, Katz JL. J Med Chem. 1994 Jul 22;37(15):2258-61.
Newman AH, Kline RH, Allen AC, Izenwasser S, George C, Katz JL. J Med Chem. 1995 Sep 29;38(20):3933-40.