(±)-Bisoprolol hemifumarate

• Supplier: Tocris Bioscience
• Catalog: 4128
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 104344-23-2
• Chemical Name: (±)-1-[4-[[2-(1-Methylethoxy)ethoxy)methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanolhemifumarate
• Formula: C18H31NO4.½C4H4O4
• Molecular Weight: 383.48
• Purity: >98 %
• Description: A selective β 1 -adrenergic antagonist. Has a K d of 2-3 nM at the β 1 receptor and a β 1 / β 2 selectivity of approximately 100-fold.

Product References

Direct labelling of myocardial beta 1-adrenoceptors. Comparison of binding - Direct labelling of myocardial beta 1-adrenoceptors. Comparison of binding

Kaumann AJ, Lemoine H. Naunyn Schmiedebergs Arch Pharmacol. 1985 Oct;331(1):27-39.

Studies on the receptor profile of bisoprolol. - Studies on the receptor profile of bisoprolol.

Klockow M, Greiner HE, Haase A, Schmitges CJ, Seyfried C. Arzneimittelforschung. 1986 Feb;36(2):197-200.

Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology - Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology

Hieble JP, Bondinell WE, Ruffolo RR Jr. J Med Chem. 1995 Sep 1;38(18):3415-44.