[D-Phe 12 ,Leu 14 ]-Bombesin

Name [D-Phe 12 ,Leu 14 ]-Bombesin
Supplier Tocris Bioscience
Catalog 1913
Prices $105.00
Sizes 1 mg
Function Type Antagonist
Cas Number 108437-88-3
Formula C75H114N22O18
Molecular Weight 1610.9
Description Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC 50 value of 2 μ M. Inhibits amylase release in vitro (IC 50 = 4 μ M) and attenuates bombesin-mediated suppression of food intake in vivo .
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Product References

[D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists. - [D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists.

Heinz-Erian P, Coy DH, Tamura M, Jones SW, Gardner JD, Jensen RT. Am J Physiol. 1987 Mar;252(3 Pt 1):G439-42.

(D-Phe12) bombesin and substance P analogues function as central bombesin - (D-Phe12) bombesin and substance P analogues function as central bombesin

Merali Z, Merchant CA, Crawley JN, Coy DH, Heinz-Erian P, Jensen RT, Moody TW. Synapse. 1988;2(3):282-7.

Bombesin receptor antagonists block the effects of exogenous bombesin but not of - Bombesin receptor antagonists block the effects of exogenous bombesin but not of

Flynn FW. Physiol Behav. 1997 Oct;62(4):791-8.