| Name | BPIPP |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3221 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 325746-94-9 |
| Chemical Name | 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione |
| Formula | C22H16BrN3O3 |
| Molecular Weight | 450.28 |
| Purity | >99 % |
| Description | Non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. Downregulates cAMP and cGMP synthesis, and suppresses cGMP accumulation in a variety of cell lines (IC 50 = 3.4 - 11.2 μ M). Inhibits GC-stimulated Cl - transport in vitro and suppresses toxin-induced intestinal fluid accumulation in vivo . |
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