BPTES

• Supplier: Tocris Bioscience
• Catalog: 3635
• Prices: $139.00, $579.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 314045-39-1
• Chemical Name: N,N'-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide
• Formula: C24H24N6O2S3
• Molecular Weight: 524.68
• Purity: >95 %
• Description: Allosteric glutaminase (GLS1) inhibitor (IC 50 = 3.3 μ M). Selective for GLS1 over GLS2 and γ -glutamyl transpeptidase. Induces cell death of P493 human lymphoma B cells in vitro and reduces tumor volume of P493 cell xenografts in mice.

Product References

Biochemical and pharmacological profile of a potent and selective endothelin - Biochemical and pharmacological profile of a potent and selective endothelin

Ishikawa K, Ihara M, Noguchi K, Mase T, Mino N, Saeki T, Fukuroda T, Fukami T, Ozaki S, Nagase T, et al.. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4892-6.

International Union of Pharmacology. XXIX. Update on endothelin receptor - International Union of Pharmacology. XXIX. Update on endothelin receptor

Davenport AP. Pharmacol Rev. 2002 Jun;54(2):219-26.

BQ-788, a selective endothelin ET(B) receptor antagonist. - BQ-788, a selective endothelin ET(B) receptor antagonist.

Okada M, Nishikibe M. Cardiovasc Drug Rev. 2002 Winter;20(1):53-66.