Name | Brain natriuretic peptide (1-32) (human) |
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Supplier | Tocris Bioscience |
Catalog | 3225 |
Prices | $379.00 |
Sizes | 1 mg |
Function Type | Agonist |
Cas Number | 124584-08-3 |
Formula | C143H244N50O42S4 |
Molecular Weight | 3464.05 |
Description | Endogenous peptide secreted from cardiac ventricles in response to volume increase and pressure overload that acts as an agonist at atrial natriuretic peptide (ANP) receptor A (NRP1). Decreases de novo collagen synthesis and increases MMP gene expression in vitro . Exhibits natriuretic, vasodilatory and lusitropic activity and inhibits the sympathetic and renin-angiotensin-aldosterone systems in vivo . |
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Tsuruda T, Boerrigter G, Huntley BK, Noser JA, Cataliotti A, Costello-Boerrigter LC, Chen HH, Burnett JC Jr. Circ Res. 2002 Dec 13;91(12):1127-34.
Wellard J, DeVente J, Hamprecht B, Verleysdonk S. Neurosci Lett. 2006 Jan 16;392(3):187-92. Epub 2005 Nov 8.
Heublein DM, Huntley BK, Boerrigter G, Cataliotti A, Sandberg SM, Redfield MM, Burnett JC Jr. Hypertension. 2007 May;49(5):1114-9. Epub 2007 Mar 19.