BRD 9876

• Supplier: Tocris Bioscience
• Catalog: 5230
• Prices: $89.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 32703-82-5
• Chemical Name: 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile
• Formula: C16H14N2
• Molecular Weight: 234.3
• Purity: >99 %
• Description: ATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC 50 = 2.2 μ M).

Product References

Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with - Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with

Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, Hideshima T, Dancik V, Majireck MM, Hussain MM, Singh S, Quiroz R, Iaconelli J, Karmacharya R, Tolliday NJ, Clemons PA, Moore MA, Stern AM, Shamji AF, Ebert BL, Golub TR, Raje NS, Scadden DT, Schreiber SL. Cell Rep. 2015 Feb 4. pii: S2211-1247(15)00030-3. doi: