Bretazenil

• Supplier: Tocris Bioscience
• Catalog: 1231
• Prices: $165.00
• Sizes: 10 mg
• Function Type: Agonist
• Cas Number: 84379-13-5
• Chemical Name: (13aS)-8-Bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylicacid1,1-dimethylethylester
• Formula: C19H20BrN3O3
• Molecular Weight: 418.28
• Purity: >98 %
• Description: Partial agonist at the GABA A benzodiazepine site (EC 50 = 10 nM at α 1 β 1 γ 2 receptors). Displays anticonvulsive activity in vivo .

Product References

Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine - Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine

Rundfeldt C, Wlaz P, Honack D, Loscher W. J Pharmacol Exp Ther. 1995 Nov;275(2):693-702.

Comparison of the novel subtype-selective GABAA receptor-positive allosteric - Comparison of the novel subtype-selective GABAA receptor-positive allosteric

Munro G, Lopez-Garcia JA, Rivera-Arconada I, Erichsen HK, Nielsen EO, Larsen JS, Ahring PK, Mirza NR. J Pharmacol Exp Ther. 2008 Dec;327(3):969-81.