BRL 15572 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3568
• Prices: $155.00, $645.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 1173022-77-9
• Chemical Name: 3-[4-(4-Chlorophenyl)piperazin-1-yl]-1,1-diphenyl-2-propanolhydrochloride
• Formula: C25H27ClN2O.HCl
• Molecular Weight: 443.42
• Description: A selective h5-HT 1D antagonist, displaying 60-fold selectivity over h5-HT 1B , and exhibiting little or no affinity for a range of other receptor types.

Product References

Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig. - Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.

Hagan JJ, Slade PD, Gaster L, Jeffrey P, Hatcher JP, Middlemiss DN. Eur J Pharmacol. 1997 Jul 23;331(2-3):169-74.

SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and - SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and

Price GW, Burton MJ, Collin LJ, Duckworth M, Gaster L, Gothert M, Jones BJ, Roberts C, Watson JM, Middlemiss DN. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20.

Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands - Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands

Schlicker E, Fink K, Molderings GJ, Price GW, Duckworth M, Gaster L, Middlemiss DN, Zentner J, Likungu J, Gothert M. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):321-7.

5-HT1-like receptors: a time to bid goodbye. - 5-HT1-like receptors: a time to bid goodbye.

Saxena PR, De Vries P, Villalon CM. Trends Pharmacol Sci. 1998 Aug;19(8):311-6.