| Name | BRL 54443 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 0699 |
| Prices | $125.00, $525.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 57477-39-1 |
| Chemical Name | 5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole |
| Formula | C14H18N2O |
| Molecular Weight | 230.31 |
| Description | A potent 5-ht 1E/1F receptor agonist (pEC 50 values are 8.5 and 8.6 respectively). Displays > 30-fold selectivity over other 5-HT and dopamine receptors (pK i values are 8.7. 8.9, 7.2, 6.9, 7.2, 5.9, 7.0, 6.5, < 6, < 6, 6.3 and 6.2 for human 5-HT 1E , 1F , 1A , 1B , 1D , 2A , 2B , 2C , 4 , 7 , D 2 and D 3 receptors respectively). Induces 5-HT 2A receptor-mediated mouse aortic contraction in vitro (pEC 50 = 6.52). Active in vivo . |
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