BS 181 dihydrochloride

Name BS 181 dihydrochloride
Supplier Tocris Bioscience
Catalog 5238
Prices $179.00, $745.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Chemical Name N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diaminedihydrochloride
Formula C22H32N6.2HCl
Molecular Weight 453.45
Purity >99 %
Description Selective cdk7 inhibitor (IC 50 = 21 nM). Displays >40-fold selectivity for cdk7 over others cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice.
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