Name | BS 181 dihydrochloride |
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Supplier | Tocris Bioscience |
Catalog | 5238 |
Prices | $179.00, $745.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Chemical Name | N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diaminedihydrochloride |
Formula | C22H32N6.2HCl |
Molecular Weight | 453.45 |
Purity | >99 % |
Description | Selective cdk7 inhibitor (IC 50 = 21 nM). Displays >40-fold selectivity for cdk7 over others cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice. |
Supplier Page | Shop |