BTS

• Supplier: Tocris Bioscience
• Catalog: 0702
• Prices: $139.00
• Sizes: 10 mg
• Function Type: Inhibitor
• Cas Number: 1576-37-0
• Chemical Name: 4-Methyl-N-(phenylmethyl)benzenesulfonamide
• Formula: C14H15NO2S
• Molecular Weight: 261.34
• Purity: >99 %
• Description: Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.

Product References

A small-molecule inhibitor of skeletal muscle myosin II. - A small-molecule inhibitor of skeletal muscle myosin II.

Cheung A, Dantzig JA, Hollingworth S, Baylor SM, Goldman YE, Mitchison TJ, Straight AF. Nat Cell Biol. 2002 Jan;4(1):83-8.

Skeletal muscle myosin cross-bridge cycling is necessary for myofibrillogenesis. - Skeletal muscle myosin cross-bridge cycling is necessary for myofibrillogenesis.

Ramachandran I, Terry M, Ferrari MB. Cell Motil Cytoskeleton. 2003 May;55(1):61-72.

Mechanism of inhibition of skeletal muscle actomyosin by - Mechanism of inhibition of skeletal muscle actomyosin by

Shaw MA, Ostap EM, Goldman YE. Biochemistry. 2003 May 27;42(20):6128-35.