| Name | BVT 948 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2177 |
| Prices | $149.00, $629.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 39674-97-0 |
| Chemical Name | 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione |
| Formula | C14H11NO3 |
| Molecular Weight | 241.25 |
| Purity | >98 % |
| Description | Non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC 50 = 0.09 - 1.7 μ M); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo . Also inhibits several cytochrome P450 isoforms (IC 50 < 10 μ M). |
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