Name | BX 430 |
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Supplier | Tocris Bioscience |
Catalog | 2035 |
Prices | $149.00, $629.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 688309-70-8 |
Chemical Name | N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea |
Formula | C15H15Br2N3O |
Molecular Weight | 413.11 |
Purity | >99 % |
Description | Selective P2X 4 allosteric antagonist (IC 50 = 0.54 μ M). Exhibits >10-fold selectivity for human P2X 4 receptors over P2X 1 , P2X 2 , P2X 3 , P2X 5 and P2X 7 receptors. Binds noncompetitively at extracellular allosteric site. Effective at human and zebrafish, but not mouse and rat P2X 4 receptors. |
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