BX 430

Name BX 430
Supplier Tocris Bioscience
Catalog 2035
Prices $149.00, $629.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 688309-70-8
Chemical Name N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea
Formula C15H15Br2N3O
Molecular Weight 413.11
Purity >99 %
Description Selective P2X 4 allosteric antagonist (IC 50 = 0.54 μ M). Exhibits >10-fold selectivity for human P2X 4 receptors over P2X 1 , P2X 2 , P2X 3 , P2X 5 and P2X 7 receptors. Binds noncompetitively at extracellular allosteric site. Effective at human and zebrafish, but not mouse and rat P2X 4 receptors.
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