C 21

Name C 21
Supplier Tocris Bioscience
Catalog 3581
Prices $265.00
Sizes 1 mg
Function Type Inhibitor
Cas Number 1229236-78-5
Formula C90H161ClN36O24
Molecular Weight 2166.94
Description Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC 50 = 1.8 μ M). Exhibits five-fold selectivity for PRMT1 over PRMT6 and >250-fold selectivity over PRMT3 and CARM1.
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Product References

A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: - A chloroacetamidine-based inactivator of protein arginine methyltransferase 1:

Obianyo O, Causey CP, Osborne TC, Jones JE, Lee YH, Stallcup MR, Thompson PR. Chembiochem. 2010 Jun 14;11(9):1219-23.

Kinetic mechanism of protein arginine methyltransferase 6 (PRMT6). - Kinetic mechanism of protein arginine methyltransferase 6 (PRMT6).

Obianyo O, Thompson PR. J Biol Chem. 2012 Feb 17;287(8):6062-71.