C 75

• Supplier: Tocris Bioscience
• Catalog: 5128
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 191282-48-1
• Chemical Name: (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylicacid
• Formula: C14H22O4
• Molecular Weight: 254.32
• Purity: >99 %
• Description: Synthetic inhibitor of fatty acid synthase (FASN); inhibits fatty acid synthesis in vitro and in vivo . Displays anorectic effects. Induces apoptosis in MCF-7 xenografts and exhibits anti-tumor activity.

Product References

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer - Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer

Zhou W, Simpson PJ, McFadden JM, Townsend CA, Medghalchi SM, Vadlamudi A, Pinn ML, Ronnett GV, Kuhajda FP. Cancer Res. 2003 Nov 1;63(21):7330-7.

The anorexigenic fatty acid synthase inhibitor, C75, is a nonspecific neuronal - The anorexigenic fatty acid synthase inhibitor, C75, is a nonspecific neuronal

Takahashi KA, Smart JL, Liu H, Cone RD. Endocrinology. 2004 Jan;145(1):184-93. Epub 2003 Sep 25.