C34

Name C34
Supplier Tocris Bioscience
Catalog 5382
Prices $109.00, $459.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 40592-88-9
Chemical Name 1-Methylethyl2-(acetylamino)-2-deoxy-α-D-glucopyranoside3,4,6-triacetate
Formula C17H27NO9
Molecular Weight 389.4
Description TLR4 inhibitor; attenuates TLR4 signaling in enterocytes and macrophages in vitro , and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis (NEC). Also suppresses LPS signaling in human ileum displaying NEC ex-vivo . Displays no significant effects on signaling via TLR2 or TLR9.
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