Calcineurin Autoinhibitory Peptide

Name Calcineurin Autoinhibitory Peptide
Supplier Tocris Bioscience
Catalog 4036
Prices $209.00
Sizes 1 mg
Function Type Inhibitor
Cas Number 148067-21-4
Formula C124H205N39O39S2
Molecular Weight 2930.34
Description Selective inhibitor of Ca 2+ -calmodulin-dependent protein phosphatase (calcineurin) (IC 50 ~ 10 μ M). Does not inhibit PP1, PP2A or CaM kinase II (IC 50 > 100 mM).
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Product References

Identification of an autoinhibitory domain in calcineurin. - Identification of an autoinhibitory domain in calcineurin.

Hashimoto Y, Perrino BA, Soderling TR. J Biol Chem. 1990 Feb 5;265(4):1924-7.

The role of the autoinhibitory domain in differential metal ion activation of - The role of the autoinhibitory domain in differential metal ion activation of

Yokoyama N, Wang JH. FEBS Lett. 1994 Jan 10;337(2):128-30.

Calcium regulation of calcineurin phosphatase activity by its B subunit and - Calcium regulation of calcineurin phosphatase activity by its B subunit and

Perrino BA, Ng LY, Soderling TR. J Biol Chem. 1995 Jan 6;270(1):340-6.