Calcipotriol

• Supplier: Tocris Bioscience
• Catalog: 1891
• Prices: $195.00, $805.00
• Sizes: 10 mg, 50 mg
• Cas Number: 112965-21-6
• Chemical Name: (1α,3β,5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol
• Formula: C27H40O3
• Molecular Weight: 412.6
• Purity: >98 %
• Description: Vitamin D 3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines.

Product References

Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: - Comparison of calcipotriol with selected metabolites and analogues of vitamin D3:

Binderup L. Pharmacol Toxicol. 1993 Apr-May;72(4-5):240-4.

Pharmacokinetics and systemic effect on calcium homeostasis of 1 - Pharmacokinetics and systemic effect on calcium homeostasis of 1

Knutson JC, LeVan LW, Valliere CR, Bishop CW. Biochem Pharmacol. 1997 Mar 21;53(6):829-37.

Antitumor properties of diastereomeric and geometric analogs of vitamin D3. - Antitumor properties of diastereomeric and geometric analogs of vitamin D3.

Wietrzyk J, Chodynski M, Fitak H, Wojdat E, Kutner A, Opolski A. Anticancer Drugs. 2007 Apr;18(4):447-57.