CALP2

• Supplier: Tocris Bioscience
• Catalog: 2561
• Prices: $139.00
• Sizes: 1 mg
• Function Type: Antagonist
• Cas Number: 261969-04-4
• Formula: C68H104N14O13S
• Molecular Weight: 1357.72
• Description: Cell-permeable calmodulin (CaM) antagonist that binds to the EF-hand/Ca 2+ -binding site. CALP2 has been demonstrated to inhibit CaM-dependant phosphodiesterase activity and increase intracellular Ca 2+ concentrations by modulating Ca 2+ -channel activity. CALP2 has also been shown to be a potent activator of alveolar macrophages.

Product References

Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast - Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast

Houtman R, Ten Broeke R, Blalock JE, Villain M, Koster AS, Nijkamp FP. J Immunol. 2001 Jan 15;166(2):861-7.

Calcium sensors as new therapeutic targets for airway hyperresponsiveness and - Calcium sensors as new therapeutic targets for airway hyperresponsiveness and

Ten Broeke R, Folkerts G, Leusink-Muis T, Van der Linde HJ, Villain M, Manion MK, De Clerck F, Blalock JE, Nijkamp FP. FASEB J. 2001 Aug;15(10):1831-3.

Specific modulation of calmodulin activity induces a dramatic production of - Specific modulation of calmodulin activity induces a dramatic production of

Broeke RT, Leusink-Muis T, Hilberdink R, Van Ark I, van den Worm E, Villain M, De Clerck F, Blalock JE, Nijkamp FP, Folkerts G. Lab Invest. 2004 Jan;84(1):29-40.