CALP3

Name CALP3
Supplier Tocris Bioscience
Catalog 2090
Prices $149.00
Sizes 1 mg
Function Type Agonist
Cas Number 261969-05-5
Formula C44H68N10O9
Molecular Weight 881.08
Description Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca 2+ -binding site. Activates phosphodiesterase in the absence of Ca 2+ and inhibits Ca 2+ -mediated cytotoxicity and apoptosis (IC 50 = 33 μ M).
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Product References

A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents - A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents

Manion MK, Su Z, Villain M, Blalock JE. FASEB J. 2000 Jul;14(10):1297-306.

Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma. - Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma.

Ten Broeke R, Brandhorst MC, Leusink-Muis T, Villain M, De Clerck F, Blalock JE, Nijkamp FP, Folkerts G. Eur J Pharmacol. 2003 Aug 22;476(1-2):151-7.