Cannabinol

Name Cannabinol
Supplier Tocris Bioscience
Catalog 3021
Prices $199.00
Sizes 10 mg
Function Type Agonist
Cas Number 521-35-7
Chemical Name 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol
Formula C21H26O2
Molecular Weight 310.43
Description CB 2 and CB 1 receptor agonist (K i values are 126 and 211 nM respectively). Inhibits adenylyl cyclase (EC 50 values are 120 and 261 nM for CB 1 and CB 2 receptors respectively) and suppresses immune cell function. Major constituent of cannabis; displays little or no psychotropic activity.
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Product References

Cannabinol derivatives: binding to cannabinoid receptors and inhibition of - Cannabinol derivatives: binding to cannabinoid receptors and inhibition of

Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanus L, Breuer A, Mechoulam R. J Med Chem. 1997 Sep 26;40(20):3228-33.

Inhibition of the cyclic AMP signaling cascade and nuclear factor binding to CRE - Inhibition of the cyclic AMP signaling cascade and nuclear factor binding to CRE

Herring AC, Koh WS, Kaminski NE. Biochem Pharmacol. 1998 Apr 1;55(7):1013-23.

Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory - Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory

Zygmunt PM, Andersson DA, Hogestatt ED. J Neurosci. 2002 Jun 1;22(11):4720-7.