( S )-4-Carboxyphenylglycine

• Supplier: Tocris Bioscience
• Catalog: 0321
• Prices: $269.00, $1,105.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 134052-73-6
• Formula: C9H9NO4
• Molecular Weight: 195.17
• Purity: >99 %
• Description: Competitive group I metabotropic glutamate receptor antagonist, with selectivity for mGlu 1a/1a over mGlu 5a/5b . ( RS )-4-Carboxyphenylglycine (Cat. No. 0321) and ( R )-4-Carboxyphenylglycine (Cat. No. 0322) also available.

Product References

Phenylglycine derivatives as new pharmacological tools for investigating the role - Phenylglycine derivatives as new pharmacological tools for investigating the role

Birse EF, Eaton SA, Jane DE, Jones PL, Porter RH, Pook PC, Sunter DC, Udvarhelyi PM, Wharton B, Roberts PJ, et al.. Neuroscience. 1993 Feb;52(3):481-8.

Competitive antagonism at metabotropic glutamate receptors by - Competitive antagonism at metabotropic glutamate receptors by

Eaton SA, Jane DE, Jones PL, Porter RH, Pook PC, Sunter DC, Udvarhelyi PM, Roberts PJ, Salt TE, Watkins JC. Eur J Pharmacol. 1993 Jan 15;244(2):195-7.

Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated - Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated

Brabet I, Mary S, Bockaert J, Pin JP. Neuropharmacology. 1995 Aug;34(8):895-903.

Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at - Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at

Doherty AJ, Collingridge GL, Jane DE. Br J Pharmacol. 1999 Jan;126(1):205-10.