Cardamonin

• Supplier: Tocris Bioscience
• Catalog: 2211
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Cas Number: 19309-14-9
• Chemical Name: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
• Formula: C16H14O4
• Molecular Weight: 270.28
• Purity: >98 %
• Description: Chalone analog that display anti-inflammatory activity. Inhibits NO and PGE 2 production from LPS- and IFN- γ -induced RAW cells and inhibits TXB 2 production via the COX-1 and COX-2 pathways. Inhibits NF- κ B activation via inhibition of I κ B α degradation and phosphorylation, I κ B kinase activation and NF- κ B nuclear translocation.

Product References

Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and - Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and

Ahmad S, Israf DA, Lajis NH, Shaari K, Mohamed H, Wahab AA, Ariffin KT, Hoo WY, Aziz NA, Kadir AA, Sulaiman MR, Somchit MN. Eur J Pharmacol. 2006 May 24;538(1-3):188-94. Epub 2006 Apr 5.

Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory - Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory

Lee JH, Jung HS, Giang PM, Jin X, Lee S, Son PT, Lee D, Hong YS, Lee K, Lee JJ. J Pharmacol Exp Ther. 2006 Jan;316(1):271-8. Epub 2005 Sep 23.

Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB - Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB

Israf DA, Khaizurin TA, Syahida A, Lajis NH, Khozirah S. Mol Immunol. 2007 Feb;44(5):673-9. Epub 2006 Jun 13.