Castanospermine

• Supplier: Tocris Bioscience
• Catalog: 5050
• Prices: $95.00, $399.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 79831-76-8
• Chemical Name: [1S-(1α,6β,7α,8β,8aβ)]-Octahydro-1,6,7,8-indolizinetetrol
• Formula: C8H15NO4
• Molecular Weight: 189.21
• Description: Potent inhibitor of α - and β -glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

Product References

Studies on the mechanism of castanospermine inhibition of alpha- and - Studies on the mechanism of castanospermine inhibition of alpha- and

Saul R, Molyneux RJ, Elbein AD. Arch Biochem Biophys. 1984 May 1;230(2):668-75.

Interference with HIV-induced syncytium formation and viral infectivity by - Interference with HIV-induced syncytium formation and viral infectivity by

Gruters RA, Neefjes JJ, Tersmette M, de Goede RE, Tulp A, Huisman HG, Miedema F, Ploegh HL. Nature. 1987 Nov 5-11;330(6143):74-7.

Inhibition of human immunodeficiency virus syncytium formation and virus - Inhibition of human immunodeficiency virus syncytium formation and virus

Walker BD, Kowalski M, Goh WC, Kozarsky K, Krieger M, Rosen C, Rohrschneider L, Haseltine WA, Sodroski J. Proc Natl Acad Sci U S A. 1987 Nov;84(22):8120-4.