Catestatin

• Supplier: Tocris Bioscience
• Catalog: 0759
• Prices: $225.00
• Sizes: 1 mg
• Function Type: Antagonist
• Cas Number: 142211-96-9
• Formula: C107H173N37O26S
• Molecular Weight: 2425.84
• Description: Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC 50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC 50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.

Product References

Novel autocrine feedback control of catecholamine release. A discrete - Novel autocrine feedback control of catecholamine release. A discrete

Mahata SK, O'Connor DT, Mahata M, Yoo SH, Taupenot L, Wu H, Gill BM, Parmer RJ. J Clin Invest. 1997 Sep 15;100(6):1623-33.

Primary structure and function of the catecholamine release inhibitory peptide - Primary structure and function of the catecholamine release inhibitory peptide

Mahata SK, Mahata M, Wakade AR, O'Connor DT. Mol Endocrinol. 2000 Oct;14(10):1525-35.