CATPB

• Supplier: Tocris Bioscience
• Catalog: 2722
• Prices: $155.00, $655.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 1322598-09-3
• Chemical Name: (S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoicacid
• Formula: C19H17ClF3NO3
• Molecular Weight: 399.79
• Purity: >98 %
• Description: FFA2 antagonist/inverse agonist (pKi = 7.87). Selective for human over mouse FFA2. Increases forskolin-induced cAMP production and inhibits acetate-induced MAPK signaling in cells expressing human FFA2.

Product References

Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally - Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally

Dziadulewicz EK, Bevan SJ, Brain CT, Coote PR, Culshaw AJ, Davis AJ, Edwards LJ, Fisher AJ, Fox AJ, Gentry C, Groarke A, Hart TW, Huber W, James IF, Kesingland A, La Vecchia L, Loong Y, Lyothier I, McNair K, O'Farrell C, Peacock M, Portmann R, Schopfer U, Yaqoob M, Zadrobilek J. J Med Chem. 2007 Aug 9;50(16):3851-6. Epub 2007 Jul 14.

Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a peripherally - Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a peripherally

Cluny NL, Keenan CM, Duncan M, Fox A, Lutz B, Sharkey KA. J Pharmacol Exp Ther. 2010 Sep 1;334(3):973-80.