CBiPES hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2663
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 856702-40-4
• Chemical Name: N-(4'-Cyano-[1,1'-biphenyl]-3-yl-N-(3-pyridinylmethyl)-ethanesulfonamidehydrochloride
• Formula: C21H19N3O2S.HCl
• Molecular Weight: 413.92
• Purity: >99 %
• Description: Selective positive allosteric modulator of the mGlu 2 receptor (IC 50 = 98.2 nM). Mimics the action of LY 379268 (Cat. No. 2453); attenuates ketamine-evoked histamine release in vivo .

Product References

Metabotropic glutamate 2 receptor potentiators: receptor modulation, - Metabotropic glutamate 2 receptor potentiators: receptor modulation,

Johnson MP, Barda D, Britton TC, Emkey R, Hornback WJ, Jagdmann GE, McKinzie DL, Nisenbaum ES, Tizzano JP, Schoepp DD. Psychopharmacology (Berl). 2005 Apr;179(1):271-83. Epub 2005 Feb 17.

Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine - Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine

Fell MJ, Katner JS, Johnson BG, Khilevich A, Schkeryantz JM, Perry KW, Svensson KA. Neuropharmacology. 2010 Mar;58(3):632-9.