CD 2314

Name CD 2314
Supplier Tocris Bioscience
Catalog 2554
Prices $205.00, $845.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 170355-37-0
Chemical Name 5-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)-3-thiophenecarboxylicacid
Formula C23H24O2S
Molecular Weight 364.5
Purity >98 %
Description Potent and selective RAR β receptor agonist (K d values are 145 and >3760 nM for RAR β and RAR α receptors respectively; no binding detected at RAR γ ). Inhibits growth of human HNSCC 22B, 183A and 22A cells (IC 50 values are 3.0, 5.7 and 8.0 μ M respectively).
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Product References

Inhibition of activation-induced apoptosis of thymocytes by all-trans- and - Inhibition of activation-induced apoptosis of thymocytes by all-trans- and

Szondy Z, Reichert U, Bernardon JM, Michel S, Toth R, Karaszi E, Fesus L. Biochem J. 1998 May 1;331 ( Pt 3):767-74.

Identification of receptor-selective retinoids that are potent inhibitors of the - Identification of receptor-selective retinoids that are potent inhibitors of the

Sun SY, Yue P, Mao L, Dawson MI, Shroot B, Lamph WW, Heyman RA, Chandraratna RA, Shudo K, Hong WK, Lotan R. Clin Cancer Res. 2000 Apr;6(4):1563-73.