CE3F4

• Supplier: Tocris Bioscience
• Catalog: 3235
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 143703-25-7
• Chemical Name: 5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde
• Formula: C11H10Br2FNO
• Molecular Weight: 351.01
• Purity: >98 %
• Description: Uncompetitive Epac1 inhibitor. Blocks Epac-induced Rap activation and prevents isoprenaline -induced autophagy flux in cardiomyocytes. Has no effect on PKA activity in the presence of cAMP.

Product References

Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of - Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of

Courilleau D, Bisserier M, Jullian JC, Lucas A, Bouyssou P, Fischmeister R, Blondeau JP, Lezoualc'h F. J Biol Chem. 2012 Dec 28;287(53):44192-202.

Exchange protein directly activated by cAMP 1 promotes autophagy during - Exchange protein directly activated by cAMP 1 promotes autophagy during

Laurent AC, Bisserier M, Lucas A, Tortosa F, Roumieux M, De Regibus A, Swiader A, Sainte-Marie Y, Heymes C, Vindis C, Lezoualc'h F. Cardiovasc Res. 2015 Jan 1;105(1):55-64.