| Name | Cercosporamide |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4448 |
| Prices | $205.00 |
| Sizes | 500 µg |
| Function Type | Inhibitor |
| Cas Number | 131436-22-1 |
| Chemical Name | (9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide |
| Formula | C16H13NO7 |
| Molecular Weight | 331.28 |
| Purity | >96 % |
| Description | Potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3 (IC 50 values are 11, 31 and 116 nM for Mnk2, JAK3 and Mnk1 respectively). Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro . Also inhibits Pkc1. Orally bioavailable. |
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