Cerestat

• Supplier: Tocris Bioscience
• Catalog: 4500
• Prices: $155.00, $645.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 137160-11-3
• Chemical Name: N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidinehydrochloride
• Formula: C20H21N3.HCl
• Molecular Weight: 339.86
• Purity: >98 %
• Description: Potent and noncompetitive NMDA receptor antagonist (IC 50 = 36 nM). Exhibits >70-fold selectivity for NMDA receptor over σ receptor. Neuroprotective in a rat model of focal ischemia.

Product References

Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. - Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives.

Reddy NL, Hu LY, Cotter RE, Fischer JB, Wong WJ, McBurney RN, Weber E, Holmes DL, Wong ST, Prasad R, et al.. J Med Chem. 1994 Jan 21;37(2):260-7.

The N-methyl-D-aspartate antagonist CNS 1102 protects cerebral gray and white - The N-methyl-D-aspartate antagonist CNS 1102 protects cerebral gray and white

Schabitz WR, Li F, Fisher M. Stroke. 2000 Jul;31(7):1709-14.