Cetirizine dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4739
• Prices: $59.00
• Sizes: 50 mg
• Function Type: Antagonist
• Cas Number: 83881-52-1
• Chemical Name: [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]aceticaciddihydrochloride
• Formula: C21H25ClN2O3.2HCl
• Molecular Weight: 461.81
• Purity: >99 %
• Description: Histamine H 1 receptor antagonist that displays selectivity over other receptors at concentrations up to 10 μ M. A non-sedating antihistamine that inhibits histamine release and eosinophil chemotaxis during secondary phase allergic response. Inhibits activation of eosinophils, neutrophils and monocytes in vivo .

Product References

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Cetirizine: actions on neurotransmitter receptors. - Cetirizine: actions on neurotransmitter receptors.

Snowman AM, Snyder SH. J Allergy Clin Immunol. 1990 Dec;86(6 Pt 2):1025-8.

Effects of cetirizine on human eosinophil and neutrophil activation in vitro. - Effects of cetirizine on human eosinophil and neutrophil activation in vitro.

Walsh GM, Moqbel R, Hartnell A, Kay AB. Int Arch Allergy Appl Immunol. 1991;95(2-3):158-62.