Cetrorelix Acetate

Name Cetrorelix Acetate
Supplier Tocris Bioscience
Catalog 2577
Prices $199.00
Sizes 1 mg
Function Type Antagonist
Cas Number 145672-81-7
Formula C70H92ClN17O14.C2H4O2
Molecular Weight 1491.11
Description Potent gonadotropin-releasing hormone (GnRH) receptor antagonist (K D = 0.202 nM, IC 50 = 1.21 nM). Suppresses production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, which inhibits ovulation. Exhibits antiproliferative effects and displays efficacy against hormone-sensitive cancers in vivo . Also exhibits anxiolytic and antidepressant activity in vivo .
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Product References

Characterization of gonadotropin-releasing hormone analogs based on a sensitive - Characterization of gonadotropin-releasing hormone analogs based on a sensitive

Beckers T, Reilander H, Hilgard P. Anal Biochem. 1997 Aug 15;251(1):17-23.

Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer. - Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer.

Grundker C, Emons G. Reprod Biol Endocrinol. 2003 Oct 7;1:65.

Effects of the LHRH antagonist Cetrorelix on the brain function in mice. - Effects of the LHRH antagonist Cetrorelix on the brain function in mice.

Telegdy G, Tanaka M, Schally AV. Neuropeptides. 2009 Jun;43(3):229-34.