CFM-2

• Supplier: Tocris Bioscience
• Catalog: 5144
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 178616-26-7
• Chemical Name: 1-(4'-Aminophenyl)-3,5-dihydro-7,8-dimethoxy-4H-2,3-benzodiazepin-4-one
• Formula: C17H17N3O3
• Molecular Weight: 311.34
• Purity: >98 %
• Description: Novel, selective non-competitive AMPA antagonist. Highly potent, long-acting anticonvulsant.

Product References

1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists. - 1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists.

Chimirri A, De Sarro G, De Sarro A, Gitto R, Grasso S, Quartarone S, Zappala M, Giusti P, Libri V, Constanti A, Chapman AG. J Med Chem. 1997 Apr 11;40(8):1258-69.

Effects of some AMPA receptor antagonists on the development of tolerance in - Effects of some AMPA receptor antagonists on the development of tolerance in

De Sarro G, Di Paola ED, Gareri P, Gallelli L, Scotto G, De Sarro A. Eur J Pharmacol. 1999 Mar 5;368(2-3):149-59.

Anticonvulsant activity and plasma level of 2,3-benzodiazepin-4-ones (CFMs) in - Anticonvulsant activity and plasma level of 2,3-benzodiazepin-4-ones (CFMs) in

De Sarro G, Rizzo M, Spagnolo C, Gitto R, De Sarro A, Scotto G, Zappala M, Chimirri A. Pharmacol Biochem Behav. 1999 Aug;63(4):621-7.