CGP 36216 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1245
• Prices: $179.00, $745.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 123691-29-2
• Chemical Name: (3-Aminopropyl)ethylphosphinicacidhydrochloride
• Formula: C5H14NO2P.HCl
• Molecular Weight: 187.6
• Purity: >99 %
• Description: Selective GABA B antagonist. Displays activity at presynaptic receptors; ineffective at GABA B postsynaptic receptors.

Product References

Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. - Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.

Froestl W, Mickel SJ, von Sprecher G, Diel PJ, Hall RG, Maier L, Strub D, Melillo V, Baumann PA, Bernasconi R, et al.. J Med Chem. 1995 Aug 18;38(17):3313-31.

CGP 36216 is a selective antagonist at GABA(B) presynaptic receptors in rat - CGP 36216 is a selective antagonist at GABA(B) presynaptic receptors in rat

Ong J, Bexis S, Marino V, Parker DA, Kerr DI, Froestl W. Eur J Pharmacol. 2001 Mar;415(2-3):191-5.