CGP 42112

Name CGP 42112
Supplier Tocris Bioscience
Catalog 1409
Prices $175.00
Sizes 1 mg
Cas Number 127060-75-7
Formula C52H69N13O11
Molecular Weight 1052.2
Description Selective, high affinity angiotensin AT 2 receptor ligand (K i = 0.24 nM). Displays agonistic properties at proximal tubule AT 2 receptors, causes Na + , K + -ATPase inhibition and sodium excretion. Antagonizes Ang-II induced contractions in rabbit aortic rings (IC 50 = 1850 nM).
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Product References

The role of angiotensin receptor subtypes in cerebrovascular regulation in the - The role of angiotensin receptor subtypes in cerebrovascular regulation in the

Naveri L. Acta Physiol Scand Suppl. 1995;630:1-48.

Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via - Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via

Hakam AC, Hussain T. Am J Physiol Renal Physiol. 2006 Jun;290(6):F1430-6. Epub 2005 Dec 27.