CGP 46381

• Supplier: Tocris Bioscience
• Catalog: 2569
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 123691-14-5
• Chemical Name: (3-Aminopropyl)(cyclohexylmethyl)phosphinicacid
• Formula: C10H22NO2P
• Molecular Weight: 219.26
• Description: Brain penetrant, selective GABA B receptor antagonist (IC 50 = 4.9 μ M).

Product References

Prolonged GABA(B) receptor-mediated synaptic inhibition in the cat spinal cord: - Prolonged GABA(B) receptor-mediated synaptic inhibition in the cat spinal cord:

Curtis DR, Lacey G. Exp Brain Res. 1998 Aug;121(3):319-33.

GABAB receptor antagonism: facilitatory effects on memory parallel those on LTP - GABAB receptor antagonism: facilitatory effects on memory parallel those on LTP

Staubli U, Scafidi J, Chun D. J Neurosci. 1999 Jun 1;19(11):4609-15.