CGP 54626 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2442
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 149184-21-4
• Chemical Name: [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl)phosphinicacid
• Formula: C18H28Cl2NO3P.HCl
• Molecular Weight: 444.76
• Purity: >96 %
• Description: A potent, selective GABA B receptor antagonist (IC 50 = 4 nM).

Product References

The action of new potent GABAB receptor antagonists in the hemisected spinal cord - The action of new potent GABAB receptor antagonists in the hemisected spinal cord

Brugger F, Wicki U, Olpe HR, Froestl W, Mickel S. Eur J Pharmacol. 1993 Apr 22;235(1):153-5.

GABA(B)-receptor subtypes assemble into functional heteromeric complexes. - GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

Kaupmann K, Malitschek B, Schuler V, Heid J, Froestl W, Beck P, Mosbacher J, Bischoff S, Kulik A, Shigemoto R, Karschin A, Bettler B. Nature. 1998 Dec 17;396(6712):683-7.