Chicago Sky Blue 6B

• Supplier: Tocris Bioscience
• Catalog: 4705
• Prices: $75.00
• Sizes: 1 g
• Function Type: Inhibitor
• Cas Number: 2610-05-1
• Chemical Name: 6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonicacid]tetrasodiumsalt
• Formula: C34H24N6Na4O16S4
• Molecular Weight: 992.79
• Description: Potent inhibitor of L-glutamate uptake into synaptic vesicles. Allosterically inhibits macrophage migration inhibitory factor (MIF) (IC 50 = 0.81 μ M); inhibits MIF proinflammatory activity.

Product References

Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that - Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that

Roseth S, Fykse EM, Fonnum F. J Neurochem. 1995 Jul;65(1):96-103.

A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF). - A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF).

Bai F, Asojo OA, Cirillo P, Ciustea M, Ledizet M, Aristoff PA, Leng L, Koski RA, Powell TJ, Bucala R, Anthony KG. J Biol Chem. 2012 Aug 31;287(36):30653-63.