Chlorisondamine diiodide

• Supplier: Tocris Bioscience
• Catalog: 4953
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 96750-66-2
• Chemical Name: 4,5,6,7-Tetrachloro-1,3-dihydro-2-methyl-2-[2-trimethylammonium)ethyl]-2H-isoindoliumdiiodide
• Formula: C14H20Cl4I2N2
• Molecular Weight: 611.95
• Purity: >99 %
• Description: An exceptionally long lasting nicotinic antagonist (IC 50 ~ 1.6 mM); blockade of central nicotinic responses induced by chlorisondamine can persist for several weeks.

Product References

The pharmacology of the nicotinic antagonist, chlorisondamine, investigated in - The pharmacology of the nicotinic antagonist, chlorisondamine, investigated in

Clarke PB, Chaudieu I, el-Bizri H, Boksa P, Quik M, Esplin BA, Capek R. Br J Pharmacol. 1994 Feb;111(2):397-405.

Blockade of nicotinic receptor-mediated release of dopamine from striatal - Blockade of nicotinic receptor-mediated release of dopamine from striatal

el-Bizri H, Clarke PB. Br J Pharmacol. 1994 Feb;111(2):406-13.

Regulation of nicotinic receptors in rat brain following quasi-irreversible - Regulation of nicotinic receptors in rat brain following quasi-irreversible

el-Bizri H, Clarke PB. Br J Pharmacol. 1994 Nov;113(3):917-25.