7-Chlorokynurenic acid sodium salt

Name 7-Chlorokynurenic acid sodium salt
Supplier Tocris Bioscience
Catalog 4436
Prices $89.00, $375.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 1263094-00-3
Chemical Name 7-Chloro-4-hydroxyquinoline-2-carboxylicacidsodiumsalt
Formula C10H5ClNNaO3
Molecular Weight 245.59
Purity >98 %
Description Sodium salt of 7-Chlorokynurenic acid (Cat.No. 0237), an NMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles.
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Product References

Behavioral and neurochemical actions of the strychnine-insensitive glycine - Behavioral and neurochemical actions of the strychnine-insensitive glycine

Kretschmer BD, Bubser M, Schmidt WJ. Eur J Pharmacol. 1995 Jun 23;280(1):37-45.

Substituted quinolines as inhibitors of L-glutamate transport into synaptic - Substituted quinolines as inhibitors of L-glutamate transport into synaptic

Bartlett RD, Esslinger CS, Thompson CM, Bridges RJ. Neuropharmacology. 1998 Jul;37(7):839-46.