| Name | Chloroquine diphosphate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 0442 |
| Prices | $45.00 |
| Sizes | 50 mg |
| Cas Number | 50-63-5 |
| Chemical Name | N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediaminediphosphatesalt |
| Formula | C18H26ClN3ยท2H3PO4 |
| Molecular Weight | 515.86 |
| Purity | >99 % |
| Description | Antimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro . Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine (Cat. No. 3977). |
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Jiang PD, Zhao YL, Deng XQ, Mao YQ, Shi W, Tang QQ, Li ZG, Zheng YZ, Yang SY, Wei YQ. Biomed Pharmacother. 2010 Nov;64(9):609-14.
Sasaki K, Tsuno NH, Sunami E, Tsurita G, Kawai K, Okaji Y, Nishikawa T, Shuno Y, Hongo K, Hiyoshi M, Kaneko M, Kitayama J, Takahashi K, Nagawa H. BMC Cancer. 2010 Jul 15;10:370.