| Name | CHR 2797 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3695 |
| Prices | $129.00, $279.00 |
| Sizes | 1 mg, 10 mg |
| Function Type | Inhibitor |
| Cas Number | 238750-77-1 |
| Chemical Name | α-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]-benzeneaceticacidcyclopentlyester |
| Formula | C21H30N2O6 |
| Molecular Weight | 406.48 |
| Purity | >98 % |
| Description | Aminopeptidase inhibitor (IC 50 values are 100, 150, 220, > 1000, > 5000, > 10000 and > 30000 nM for LAP, PuSA, aminopeptidase N, aminopeptidase B, PILSAP, LTA 4 hydrolase and MetAP2 respectively). Potently inhibits tumor cell proliferation in a variety of tumor cell lines in vitro and in vivo . |
| Supplier Page | Shop |
Krige D, Needham LA, Bawden LJ, Flores N, Farmer H, Miles LE, Stone E, Callaghan J, Chandler S, Clark VL, Kirwin-Jones P, Legris V, Owen J, Patel T, Wood S, Box G, Laber D, Odedra R, Wright A, Wood LM, Eccles SA, Bone EA, Ayscough A, Drummond AH. Cancer Res. 2008 Aug 15;68(16):6669-79.
Moore HE, Davenport EL, Smith EM, Muralikrishnan S, Dunlop AS, Walker BA, Krige D, Drummond AH, Hooftman L, Morgan GJ, Davies FE. Mol Cancer Ther. 2009 Apr;8(4):762-70.