| Name | CHR 6494 trifluoroacetate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3595 |
| Prices | $149.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 1458630-17-5 |
| Chemical Name | 3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-aminetrifluoroacetate |
| Formula | C16H16N6.CF3CO2H |
| Molecular Weight | 406.36 |
| Purity | >98 % |
| Description | Potent and selective haspin kinase inhibitor (IC 50 = 2 nM). Selective over 27 other protein kinases including Aurora B kinase. Induces cell cycle arrest at G 2 /M, inhibits cell proliferation and promotes apoptosis in multiple cancer cell lines. Inhibits angiogenesis ex vivo and attenuates tumor growth of HCT-116 xenografts in rats. |
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