Chromanol 293B

• Supplier: Tocris Bioscience
• Catalog: 5326
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Blocker
• Cas Number: 163163-23-3
• Chemical Name: trans-N-[6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide
• Formula: C15H20N2O4S
• Molecular Weight: 324.39
• Purity: >99 %
• Description: Blocker of the slow delayed rectifier K + current (I Ks ) (IC 50 = 1-10 μ M). Also blocks the CFTR chloride current (I CFTR ) (IC 50 = 19 μ M). (-)-[3 R ,4 S ]-Chromanol 293B (Cat. No. 1475) also available.

Product References

Time-dependent block of the slowly activating delayed rectifier K(+) current by - Time-dependent block of the slowly activating delayed rectifier K(+) current by

Fujisawa S, Ono K, Iijima T. Br J Pharmacol. 2000 Mar;129(5):1007-13.

Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs), - Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs),

Bachmann A, Quast U, Russ U. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jun;363(6):590-6.

Chromanol 293B inhibits slowly activating delayed rectifier and transient outward - Chromanol 293B inhibits slowly activating delayed rectifier and transient outward

Sun ZQ, Thomas GP, Antzelevitch C. J Cardiovasc Electrophysiol. 2001 Apr;12(4):472-8.